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A pharmacist gives Jennifer Haller the first shot, March 16, 2020, in the first-stage safety study clinical trial of a potential vaccine for COVID-19, at the Kaiser Permanente Washington Health Research Institute in Seattle.

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The world's biggest COVID-19 vaccine test got underway July 27 with the first of 30,000 planned volunteers. The experimental vaccine is made by the National Institutes of Health and Moderna Inc., and it's one of several candidates in the final stretch of the global vaccine race.

Dr. Noubar Afeyan, co-founder and chairman of Moderna Therapeutics, said the biotech firm would become the first U.S. company to enter Phase III of a clinical trial for a potential coronavirus vaccine.

Over 10 000 health workers in Africa infected with COVID-19

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Inadequate access to personal protective equipment or weak infection prevention and control measures raise the risk of health worker infection.

The World Health Organization's Regional Office For Africa (WHO) has warned of the threat posed by COVID-19 to health workers across Africa. More than 10 000 health workers in the 40 countries which have reported on such infections have been infected with COVID-19 so far, a sign of the challenges medical staff on the frontlines of the outbreak face.

COVID-19 rashes: How your skin can be a sign of the virus

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One of the most widely talked about skin findings related to coronavirus infection is the so-called "COVID toes" syndrome. Dr. Ginette Okoye, ...

As the pandemic continues, doctors and researchers are learning more about the symptoms of COVID-19. And, as it turns out, some of them -- like rashes -- may be easy to see.

Wave of promising study results raise hopes for coronavirus vaccines

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The Oxford/AstraZeneca vaccine is one of 150 in development globally, but is considered the most advanced. Late-stage trials have begun in Brazil and South Africa and are due to start in the United States, where the infection prevalence is highest.

Early data from trials of three potential COVID-19 vaccines released on Monday, including a closely-watched candidate from Oxford University, increased confidence that a vaccine can train the immune system to recognize and fight the novel coronavirus without serious side effects.

Men should limit alcohol to 1 drink a day, experts say

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The proposed advice shouldn’t be interpreted to mean that not having a drink on Thursday means you can have two on Friday, ....

If you decide to have an alcoholic drink, limiting yourself to one a day is best — whether you’re a man or woman.

How Covid-19 can damage the brain

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These findings suggest that Covid-19 has a “neurotropic inclination, meaning that it attacks neurons”, Lledo continued. The best-known neurotropic virus is rabies, which attacks the central nervous system almost exclusively. The fact that Covid-19 is primarily a respiratory illness in no way prevents it from having this neurological aspect.

Not only does Covid-19 damage the lungs, heart and kidneys, it can also cause severe brain damage – with patients suffering neurological conditions including paranoia and hallucinations, a British scientific study has revealed.

This 2020 electron microscope made available by the U.S. Centers for Disease Control and Prevention image shows the spherical coronavirus particles from the first U.S. case of COVID-19. Two new studies published online Monday, June 29 in the New England Journal of Medicine, suggest more than 250 U.S. children have developed a serious inflammatory condition linked to the coronavirus and while most recovered after intensive-care treatment, the potential for long-term or permanent damage is unknown. (C.S. Goldsmith, A. Tamin/CDC via AP)

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Digestive symptoms including nausea and diarrhea are common. Some children may have symptoms resembling Kawasaki disease, a rare condition in children that can cause swelling and heart problems.

At least 285 U.S. children have developed a serious inflammatory condition linked to the coronavirus and while most recovered, the potential for long-term or permanent damage is unknown, two new studies suggest.

WHO Director-General Tedros Adhanom Ghebreyesus

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"The reality is this is not close to being over," Tedros told reporters. "Globally, the pandemic is actually speeding up."

Six months after the World Health Organization (WHO) first identified a cluster of atypical pneumonia cases at a hospital in Wuhan, China, the number of people newly infected with the SARS-CoV-2 coronavirus is rising rapidly.

CanSino's COVID-19 vaccine candidate approved for military use in China

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The Ad5-nCoV is one of China’s eight vaccine candidates approved for human trials at home and abroad for the respiratory disease caused by the new coronavirus. The shot also won approval for human testing in Canada.

China’s military has received the greenlight to use a COVID-19 vaccine candidate developed by its research unit and CanSino Biologics (6185.HK) after clinical trials proved it was safe and showed some efficacy, the company said on Monday.

Gilead prices COVID-19 drug remdesivir at $2,340 per patient in developed nations

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The price tag is slightly below the range of $2,520 to $2,800 suggested last week by U.S. drug pricing research group the Institute for Clinical and Economic Review (ICER) after British researchers said they found that the cheap, widely available steroid dexamethasone significantly reduced mortality among severely ill COVID-19 patients.

Gilead Sciences Inc on Monday priced its COVID-19 antiviral remdesivir at $2,340 per patient for wealthier nations and agreed to send nearly all of its supply of the drug to the United States over the next three months.

Chinese firm says coronavirus vaccine candidate shows promise in human test

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Chinese companies and researchers have been allowed to test eight vaccine candidates in humans at home and abroad, making China a major front-runner in the race to develop a shot against the virus that has killed nearly 500,000 people globally.

China National Biotec Group (CNBG) said on Sunday that early human test results for a coronavirus vaccine candidate suggested it could be safe and effective, the second vaccine candidate from the firm to show encouraging results in a clinical trial.

Military personnel are seen at a drive-through coronavirus disease (COVID-19) testing facility in Hyde Park, following the outbreak of the coronavirus disease, London, Britain, June 11, 2020. File image

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“Saliva testing could potentially make it even easier for people to take coronavirus tests at home, without having to use swabs,” said Health Secretary Matt Hancock.

A weekly coronavirus testing regime using a “no-swab” saliva test is being trialled in Southampton, southern England, and could result in a simpler and quicker way to detect outbreaks of the virus, the British government said on Monday.

WHO moves to update COVID-19 guidance after 'great news' in drug study

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Trial results announced on Tuesday showed dexamethasone, used since the 1960s to reduce inflammation in diseases such as arthritis, cut death rates by around a third among the most severely ill COVID-19 patients admitted to hospital.

The World Health Organization (WHO) said it was moving to update its guidelines on treating people stricken with COVID-19 to reflect results of a clinical trial that showed a cheap, common steroid can help save critically ill patients.

A close-up of a box of Dexamethasone tablets in a pharmacy on June 16, 2020, in Cardiff, United Kingdom. Results of a trial announced today have shown that Dexamethasone, a cheap and widely used steroid drug which is used to reduce inflammation, reduced death rates by around a third in the most severely ill COVID-19 patients who were admitted to the hospital.A close-up of a box of Dexamethasone tablets in a pharmacy on June 16, 2020, in Cardiff, United Kingdom. Results of a trial announced today have shown that Dexamethasone, a cheap and widely used steroid drug which is used to reduce inflammation, reduced death rates by around a third in the most severely ill COVID-19 patients who were admitted to the hospital. Matthew Horwood/Getty Images

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Meanwhile, the drug also seemed to benefit patients who required oxygen assistance without mechanical ventilation, reducing deaths in this group by about 20%.

As the world awaits a COVID-19 vaccine, researchers studying possible treatments have found a commonly used steroid called dexamethasone that might help save one-third of patients who end up on ventilators.

The agency determined that the legal criteria for issuing an EUA are no longer met. Based on its ongoing analysis of the EUA and emerging scientific data, the FDA determined that chloroquine and hydroxychloroquine are unlikely to be effective in treating COVID-19 for the authorized uses in the EUA.

The U.S. Food and Drug Administration (FDA) has revoked the emergency use authorization (EUA) that allowed for chloroquine phosphate and hydroxychloroquine sulfate donated to the Strategic National Stockpile to be used to treat certain hospitalized patients with COVID-19 when a clinical trial was unavailable, or participation in a clinical trial was not feasible.

Coronavirus patients most infectious when they first feel unwell: WHO

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Dr. Mike Ryan, WHO’s top emergencies expert, said that the novel coronavirus lodges in the upper respiratory tract, making it easier to transmit by droplets than related viruses such as SARS or MERS, which are in the lower tract.

Studies show people with the coronavirus are most infectious just at the point when they first begin to feel unwell, World Health Organization (WHO) experts said on Tuesday.

WHO Director General Tedros Adhanom Ghebreyesus . File image

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More than 136,000 new cases were reported worldwide on Sunday, the most in a single day so far, he said. Nearly 75% of them were reported from 10 countries, mostly in the Americas and South Asia.

New coronavirus cases had their biggest daily increase ever as the pandemic worsens globally and has yet to peak in central America, the World Health Organization (WHO) said on Monday, urging countries to press on with efforts to contains the virus.

A scientist examines COVID-19 infected cells during research for a vaccine against the coronavirus disease (COVID-19) at a laboratory of BIOCAD biotechnology company in Saint Petersburg, Russia May 20, 2020. REUTERS/Anton Vaganov

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GAVI is a public-private partnership backed by the Bill & Melinda Gates Foundation, the WHO, the World Bank, UNICEF and others, which arranges bulk buys to reduce vaccine costs for poor countries.

The GAVI vaccines alliance said on Thursday it had raised $8.8 billion from international donor governments, companies and philanthropic foundations to fund its immunisation programmes through to 2025.

Eli Lilly starts human study of potential COVID-19 antibody treatment

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Rival Regeneron Pharmacuticals Inc has said it plans to start clinical studies in June to test its antibody cocktail treatment for the new coronavirus and is aiming to have hundreds of thousands of preventative doses available by the end of August.

Eli Lilly and Co said on Monday it had started an early-stage trial to test its potential treatment for COVID-19, in the world’s first study of an antibody treatment against the disease.

UN virus therapy trial pauses hydroxychloroquine testing

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Hydroxychloroquine and chloroquine are approved for treating lupus and rheumatoid arthritis and for preventing and treating malaria, but no large rigorous tests have found them safe or effective for preventing or treating COVID-19.

The World Health Organization said Monday that it will temporarily drop hydroxychloroquine — the anti-malarial drug U.S. President Trump says he is taking — from its global study into experimental COVID-19 treatments, saying that its experts need to review all available evidence to date.

WHO warns of 'second peak' in areas where COVID-19 declining

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Ryan said epidemics often come in waves, which means that outbreaks could come back later this year in places where the first wave has subsided. There was also a chance that infection rates could rise again more quickly if measures to halt the first wave were lifted too soon.

Countries where coronavirus infections are declining could still face an “immediate second peak” if they let up too soon on measures to halt the outbreak, the World Health Organization said on Monday.

Apple and Google launch digital contact tracing system. Image credit -firstpost

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Working together to design the system means that Android and iPhone applications, as well as applications from different states, will be able to recognize one another.

Apple and Google are getting into the digital contact tracing space, the companies jointly announced Wednesday.

Members of the media witness a demonstration of new measures involving UV-C light technology to disinfect a subway car during the coronavirus pandemic at the Corona Maintenance Facility, May 19, 2020, in the Queens borough of New York.Members of the media witness a demonstration of new measures involving UV-C light technology to disinfect a subway car during the coronavirus pandemic at the Corona Maintenance Facility, May 19, 2020, in the Queens borough of New York. Frank Franklin II/AP

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People are exposed to a coronavirus through mucus membranes of the eyes, nose and mouth via respiratory droplets.

Hailing it as a tested killer of the novel coronavirus, New York City transit officials announced on Tuesday that they are launching a pilot program using ultraviolet light to disinfect its subway cars and buses.

Coronavirus vaccine from Moderna appears safe, shows promise in data from eight people

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Overall, the study showed the vaccine was safe and all study participants produced antibodies against the virus.

Moderna Inc’s experimental COVID-19 vaccine, the first to be tested in the United States, produced protective antibodies in a small group of healthy volunteers, according to very early data released by the biotech company on Monday.

Director-General of WHO, Dr. Tedros Adhanom Ghebreyesus

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The EU resolution proposes that the independent evaluation should be initiated “at the earliest appropriate moment” and should, among other issues, examine “the actions of WHO and their timelines pertaining to the COVID-19 pandemic.”

The European Union and other countries on Monday called for an independent evaluation of the World Health Organization’s response to the coronavirus pandemic “to review experience gained and lessons learned.”

8 more sailors aboard US ship test positive a 2nd time

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On Saturday, a Navy official confirmed eight additional sailors had tested positive again. A day earlier the Navy had said in a statement that five had tested positive a second time.

Eight more sailors aboard the USS Theodore Roosevelt have tested positive again for the coronavirus, raising to 13 the number who appear to have become infected a second time while serving aboard the sidelined aircraft carrier.

A cashier wearing a face shield bags groceries for a customer at the Local Market Foods store in Chicago, April, 8, 2020. AFP photo

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Case studies that traced back COVID-19 outbreaks at the beginning of the pandemic, have found that the main sources of infections in the community lead back to the workplace, public transportation, social gatherings, and restaurants — indoor environments, with limited air circulation, and many people spending a prolonged period of time in the same place.

Recommendations on how to protect ourselves from contracting the virus that causes COVID-19 are everywhere, like washing your hands, wearing a mask, and staying at least 6 feet away from people outside your home. But not all risks are created equal; home, public transportation and the grocery store all have different challenges.

A pharmacist gives Jennifer Haller, left, the first shot in the first-stage safety study clinical trial of a potential vaccine for COVID-19, the disease caused by the new coronavirus, Monday, March 16, 2020, at the Kaiser Permanente Washington Health Research Institute in Seattle. File image

Health

The European Medicines Agency predicted that there could be licensed drugs to treat the new coronavirus in the next few months and that a vaccine might even be approved in early 2021, in a “best-case scenario.”

The European Medicines Agency predicted that there could be licensed drugs to treat the new coronavirus in the next few months and that a vaccine might even be approved in early 2021, in a “best-case scenario.”

What do studies on new coronavirus mutations tell us?

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Here’s what experts are saying about those findings and how they might affect the COVID-19 pandemic and efforts to develop vaccines and treatments.

A series of studies of the genomes of thousands of samples of the new coronavirus SARS-CoV-2 show that it is mutating and evolving as it adapts to its human hosts.

FDA approves remdesivir to treat COVID-19

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The agency said the drug has not been approved as a general treatment for COVID-19. Rather, it is only intended for emergency use on severely ill patients who have been hospitalized.

 The U.S. Food and Drug Administration on Friday granted emergency use authorization for the antiviral remdesivir to treat COVID-19.

COVID-19: Vaccine trials ongoing in 5 African countries

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In a joint briefing online with doctors at Shanghai hospital, the Africa CDC said that in comparison to the rest of the world there were very few treatments happening on the continent.

The Africa Centre for Disease Control (CDC) has outlined some of the trials going on for Covid-19 treatment and vaccination in Africa.

Data on Gilead drug raises hopes in pandemic fight, Fauci calls it 'highly significant'

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Remdesivir, which previously failed as a treatment for Ebola, is being tried against COVID-19 because it is designed to disable the mechanism by which certain viruses make copies of themselves and potentially overwhelm their host’s immune system.

The top U.S. infectious disease official said Gilead Sciences Inc’s experimental antiviral drug remdesivir will become the standard of care for COVID-19 after early results from a key clinical trial on Wednesday showed it helped patients recover more quickly from the illness caused by the coronavirus.

Elisa Granato was the first volunteer to be injected

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Although the university has urged caution when it comes to mapping out a firm timeline for when the vaccine -- called ChAdOx1 nCoV-19 -- would be in development, a best-case scenario could see for the vaccine’s efficacy determined by fall 2020.

The first patients have been enrolled in human trials for a coronavirus vaccine at the historic University of Oxford after the U.K.’s Health Secretary said the country would be “throwing everything” behind the project.

Revealing S. Korean studies show antibodies could thwart COVID-19 reinfection, spread

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Researchers were initially concerned that antibodies might not kill the virus, because roughly half of patients had both antibodies and a current COVID-19 infection.

Results from two new South Korean studies shed light on whether antibodies will be a reliable form of protection against COVID-19 for those who have recovered from the disease.

Explainer: What is contact tracing and how can it help fight the new coronavirus?

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Hundreds of thousands of investigators will be needed to do contact tracing in the United States once stay-at-home orders lift, Rutherford said.

Contact tracing has been used for decades to control the spread of infectious diseases. The basic idea is simple: track down infected people, then find everyone who has been near them and encourage those people to stay home until it is clear they are not sick.

Scientists around the world are racing against time to develop a coronavirus vaccine [Thomas Peter/Reuters]

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Experimental COVID-19 treatments to go ahead in China as it grapples with imported cases from neighbouring Russia.

China has approved early-stage human tests for two experimental coronavirus vaccines as it battles to contain imported cases and prevent a second wave of COVID-19.

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